Jesseriah McCree

Scarlet Lord Jesseriah McCree is a level 57 elite human NPC located at the Scarlet Enclave town of New Avalon. Along with the Scarlet Crusaders, he fights the neverending waves of ghouls attacking the town.

Strategy
A common tactic players have used to kill him with is by using Death Grip and kiting him to Crypt of Remembrance and letting the guards there kill him. Or they can kill the other Scarlet Soldiers and let the massive phase 2 Scarlet Ghoul army eventually overwhelm him. However, Jesseriah McCree's Holy Wrath ability allows him to instantly wipe out large numbers (20 or so) of non player undead surrounding him. He is moderately difficult to solo at or below his level but with additional players and/or levels he gets much easier to defeat. The main point is to wipe out his adds as quickly as possible.

When dealing with his knock back effect(Cleave) you can either get around it by bracing yourself against a wall or use it to your advantage by steering the knockbacks to remove you from the range of his adds. His adds have a short leesh. Jesseriah McCree however, does not.

It would be prudent to have as much healing as possible, such as improved rune tap and using attacks such as Unholy Strike, Icy Touch and Death Strike.

Trivia
He is most likely a reference to Jesse McCree the Lead Level Designer: Exterior for Blizzard Entertainment.